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Article

Comparative analysis of phenotype and gene expression in Saccharomyces cerevisiae grown in solid versus liquid culture formats.

BMC microbiology - 3 Mar 2026

Liu Jinqi, Wang Qi, Lin Jing, Lei Jianpeng, Xu Zhenyuan, Dai Jian, Wang Kai

Abstract excerpt

BACKGROUND: Saccharomyces cerevisiae is a pivotal model organism in biological research. In practice, the choice between solid and liquid formats of the same culture medium is often based on convenience, with an implicit assumption that the physical format (solid vs. liquid) of the medium has minimal impact on core physiological outcomes. This study systematically tested this assumption by comparing the...

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PMID: 41776389
DOI: 10.1186/s12866-026-04855-6
PMCID: PMC13063483

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