Article
Mutations in Drosophila crinkled/Myosin VIIA disrupt denticle morphogenesis.
Developmental biology - 1 Feb 2021
Sallee Jennifer L, Crawford Janice M, Singh Vinay, Kiehart Daniel P
Abstract excerpt
Actin filament crosslinking, bundling and molecular motor proteins are necessary for the assembly of epithelial projections such as microvilli, stereocilia, hairs, and bristles. Mutations in such proteins cause defects in the shape, structure, and function of these actin - based protrusions. One protein necessary for stereocilia formation, Myosin VIIA, is an actin - based motor protein conserved throughout...
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