Article
Genetically predicted circulating protein biomarkers and ovarian cancer risk.
Gynecologic oncology - 1 Feb 2021
Considine Daniel P C, Jia Guochong, Shu Xiang, Schildkraut Joellen M, Pharoah Paul D P, Zheng Wei, Kar Siddhartha P
Abstract excerpt
OBJECTIVE: Most women with epithelial ovarian cancer (EOC) are diagnosed after the disease has metastasized and survival in this group remains poor. Circulating proteins associated with the risk of developing EOC have the potential to serve as biomarkers for early detection and diagnosis. We integrated large-scale genomic and proteomic data to identify novel plasma proteins associated with EOC risk. METHODS: We...
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