Article
Comparative analysis of transcriptomic profile, histology, and IDH mutation for classification of gliomas.
Scientific reports - 26 Nov 2020
Tran Paul M H, Tran Lynn K H, Nechtman John, Dos Santos Bruno, Purohit Sharad, Satter Khaled Bin, Dun Boying, Kolhe Ravindra, Sharma Suash, Bollag Roni, She Jin-Xiong
Abstract excerpt
Gliomas are currently classified through integration of histology and mutation information, with new developments in DNA methylation classification. However, discrepancies exist amongst the major classification methods. This study sought to compare transcriptome-based classification to the established methods. RNAseq and microarray data were obtained for 1032 gliomas from the TCGA and 395 gliomas from REMBRANDT....
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