Article
A Retrospective Genomic Landscape of 661 Young Adult Glioblastomas Diagnosed Using 2016 WHO Guidelines for Central Nervous System Tumors.
The oncologist - 5 Jan 2024
Haberberger James F, Pegram Worthy, Britt Nicholas, Schiavone Kelsie, Severson Eric, Sharaf Radwa, Albacker Lee A, Williams Erik, Lechpammer Mirna, Hemmerich Amanda, Lin Douglas, Huang Richard S P, Hiemenz Matthew, Elvin Julia, Graf Ryon, Lesser Glenn, Kram David, Strowd Roy, Bi Wenya Linda, Ramkissoon Lori A, Cohen Michael B, Reddy Prasanth, Creeden James, Ross Jeffrey S, Alexander Brian M, Ramkissoon Shakti H
Abstract excerpt
The authors present a cohort of 661 young adult glioblastomas diagnosed using 2016 WHO World Health Organization Classification of Tumors of the Central Nervous System, utilizing comprehensive genomic profiling (CGP) to explore their genomic landscape and assess their relationship to currently defined disease entities. This analysis explored variants with evidence of pathogenic function, common copy number...
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