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Article

Unveiling divergent treatment prognoses in IDHwt-GBM subtypes through multiomics clustering: a swift dual MRI-mRNA model for precise subtype prediction.

Journal of translational medicine - 18 Jun 2024

Ji Qiang, Zheng Yi, Zhou Lili, Chen Feng, Li Wenbin

Abstract excerpt

BACKGROUND: IDH1-wildtype glioblastoma multiforme (IDHwt-GBM) is a highly heterogeneous and aggressive brain tumour characterised by a dismal prognosis and significant challenges in accurately predicting patient outcomes. To address these issues and personalise treatment approaches, we aimed to develop and validate robust multiomics molecular subtypes of IDHwt-GBM. Through this, we sought to uncover the distinct...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38890658
DOI: 10.1186/s12967-024-05401-6
PMCID: PMC11186189

Genes

IDH1
PAM

Provenance

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