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Article

TBP-Related Factor 2 as a Trigger for Robertsonian Translocations and Speciation.

International journal of molecular sciences - 23 Nov 2020

Cherezov Roman O, Vorontsova Julia E, Simonova Olga B

Abstract excerpt

Robertsonian (centric-fusion) translocation is the form of chromosomal translocation in which two long arms of acrocentric chromosomes are fused to form one metacentric. These translocations reduce the number of chromosomes while preserving existing genes and are considered to contribute to speciation. We asked whether hypomorphic mutations in genes that disrupt the formation of pericentromeric regions could lead...

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Identifiers

PMID: 33238614
DOI: 10.3390/ijms21228871
PMCID: PMC7700478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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