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Article

The Drosophila Malpighian tubule as a model for mammalian tubule function

3 Jul 2019

Abstract excerpt

PURPOSE OF REVIEW: Studies of the genetic model organism, Drosophila melanogaster, have unraveled molecular pathways relevant to human physiology and disease. The Malpighian tubule, the Drosophila renal epithelium, is described here, including tools available to study transport; conserved transporters, channels, and the signaling pathways regulating them; and fly models of kidney stone disease. RECENT FINDINGS:...

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PMID: 31268918
DOI: 10.1097/mnh.0000000000000521

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