Correlation of tumor necrosis factor-α -308G>A polymorphism with susceptibility, clinical manifestations and severity in Behçet syndrome: evidences from an Italian genetic case-control study

Abstract excerpt

<h4>Background: </h4> The tumor necrosis factor (TNF)α is a multifunctional proinflammatory cytokine, implicated in a variety of diseases, including Behçet syndrome (BS), a rare vasculitis with a wide spectrum of clinical manifestations. The aim of the present study was to investigate the association between a functional drug-response TNFα gene polymorphism (at the positions of -308; rs1800629) and both disease su...

Topics

Open a Topic to create a Post that cites this publication.

• Behcet Syndrome
• Case-Control Studies
• Genetic Predisposition to Disease
• Italy
• Ocular Diseases and Behçet’s Syndrome
• Polymorphism, Single Nucleotide
• Systemic Lupus Erythematosus Research
• Tumor Necrosis Factor-alpha

Identifiers and source

Literature Corpus work

b78e1941-3d99-5624-b41c-f6d6076ec168

DOI

10.21203/rs.2.19801/v1