Article
No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach.
Diabetologia - 1 Oct 2011
Pfister R, Barnes D, Luben R, Forouhi N G, Bochud M, Khaw K-T, Wareham N J, Langenberg C
Abstract excerpt
AIMS/HYPOTHESIS: Epidemiological and experimental evidence suggests that uric acid has a role in the aetiology of type 2 diabetes. Using a Mendelian randomisation approach, we investigated whether there is evidence for a causal role of serum uric acid for development of type 2 diabetes. METHODS: We examined the associations of serum-uric-acid-raising alleles of eight common variants recently identified in...
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