Article
Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota.
Communications biology - 18 Nov 2020
Ishida Sachiko, Kato Kumiko, Tanaka Masami, Odamaki Toshitaka, Kubo Ryuichi, Mitsuyama Eri, Xiao Jin-Zhong, Yamaguchi Rui, Uematsu Satoshi, Imoto Seiya, Miyano Satoru
Abstract excerpt
Numerous host extrinsic and intrinsic factors affect the gut microbiota composition, but their cumulative effects do not sufficiently explain the variation in the microbiota, suggesting contributions of missing factors. The Japanese population possesses homogeneous genetic features suitable for genome-wide association study (GWAS). Here, we performed GWASs for human gut microbiota using 1068 healthy Japanese...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.