Article

Environmental factors dominate over host genetics in shaping human gut microbiota composition

2017-06-16

Abstract excerpt

Human gut microbiome composition is shaped by multiple host intrinsic and extrinsic factors, but the relative contribution of host genetic compared to environmental factors remains elusive. Here, we genotyped a cohort of 696 healthy individuals from several distinct ancestral origins and a relatively common environment, and demonstrate that there is no statistically significant association between microbiome compo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 24617857-7d70-598b-9747-107577daffde
DOI: 10.1101/150540

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Environmental factors dominate over host genetics in shaping human gut microbiota compositionDOI 10.1101/150540Read

Environment dominates over host genetics in shaping human gut microbiota.Semantic proximity Read

Host genetic variation impacts microbiome composition across human body sites.Semantic proximity Read

The Dutch Microbiome Project defines factors that shape the healthy gut microbiomeSemantic proximity Read

The predictive power of the microbiome exceeds that of genome-wide association studies in the discrimination of complex human diseaseSemantic proximity Read

Improving causality in microbiome research: can human genetic epidemiology help?Semantic proximity Read

Challenges and future directions for studying effects of host genetics on the gut microbiome.Semantic proximity Read

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individualsSemantic proximity Read

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohortSemantic proximity Read

Environment dominates over host genetics in shaping human gut microbiotaSemantic proximity Read

The Relationship Between the Human Genome and Microbiome Comes into View.Semantic proximity Read

Polygenic Risk Links to the Gut Microbiome: The MAGI CatalogSemantic proximity Read

A Comprehensive Assessment of Demographic, Environmental and Host Genetic Associations with Gut Microbiome Diversity in Healthy IndividualsSemantic proximity Read