Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wilson disease, ABCC2 c.3972C > T polymorphism and primary liver cancers: suggestions from a familial cluster.

BMC medical genetics - 18 Nov 2020

Brandi Giovanni, Rizzo Alessandro, Deserti Marzia, Relli Valeria, Indio Valentina, Bin Sofia, Pariali Milena, Palloni Andrea, De Lorenzo Stefania, Tovoli Francesco, Tavolari Simona

Abstract excerpt

BACKGROUND: Polymorphisms in genes modulating xenobiotics metabolism, in particular the ABCC2 c.3972C > T single nucleotide polymorphism (SNP) at exon 28, have been suggested to increase primary liver cancer (PLC) risk. Conversely, the occurrence of PLCs in Wilson disease patients is a rare event, in contrast with the occurrence observed in other chronic liver diseases. Here we report the clinical case of five...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asbestos
Share to Cholangiocarcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cigarette Smoking

Share to Hepatolenticular Degeneration

Share to Liver Cirrhosis

Share to Multidrug Resistance-Associated Protein 2

Share to Multidrug Resistance-Associated Proteins

Share to Siblings

Source

Open in PubMed Open full text

Identifiers

PMID: 33208122
DOI: 10.1186/s12881-020-01165-0
PMCID: PMC7673086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wilson disease, ABCC2 c.3972C > T polymorphism and primary liver cancers: suggestions from a familial cluster.PMID 33208122Read ↗

Association of the c.3972C>T variant of the multidrug resistance-associated protein 2 Gene (MRP2/ABCC2) with susceptibility to bile duct cancer.Semantic proximity Read ↗

Alcohol-related cancers and genetic susceptibility in Europe: the ARCAGE project: study samples and data collection.Semantic proximity Read ↗

Hypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes.Semantic proximity Read ↗

Risk of HCC: genetic heterogeneity and complex genetics.Semantic proximity Read ↗

Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives.Semantic proximity Read ↗

Interplay Of Serum Bilirubin and Tobacco Smoking with Lung and Head and Neck Cancers in a Diverse, EHR-linked Los Angeles BiobankSemantic proximity Read ↗

Carcinogens that induce the A:T > T:A nucleotide substitutions in the genome.Semantic proximity Read ↗

Interplay Of Serum Bilirubin and Tobacco Smoking with Lung and Head and Neck Cancers in a Diverse, EHR-linked Los Angeles BiobankSemantic proximity Read ↗

PBC triggers in water reservoirs, coal mining areas and waste disposal sites: from Newcastle to New York.Semantic proximity Read ↗

Genetic risk of cholangiocarcinoma is linked to the autophagy gene <i>ATG7</i>Semantic proximity Read ↗

A case-control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk in Cantonese.Semantic proximity Read ↗

Genetic susceptibility of lung cancer associated with common variants in the 3' untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.