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Article

Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives.

Gastroenterology - 1 Dec 2003

Elmberg Maria, Hultcrantz Rolf, Ekbom Anders, Brandt Lena, Olsson Sigvard, Olsson Rolf, Lindgren Stefan, Lööf Lars, Stål Per, Wallerstedt Sven, Almer Sven, Sandberg-Gertzén Hanna, Askling Johan

Abstract excerpt

BACKGROUND & AIMS: Iron overload may be carcinogenic. Patients with hereditary hemochromatosis (HH) are reportedly at a 20-200-fold risk of intrahepatic cancer, but the reported risks for nonhepatobiliary cancers are conflicting. The risk of cancer in heterozygous individuals (estimated allele frequency, 1/10 to 1/20) is unknown. This study aimed to better assess these risks. METHODS: We performed a...

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Identifiers

PMID: 14724826
DOI: 10.1053/j.gastro.2003.09.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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