Article
A case-control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk in Cantonese.
Carcinogenesis - 1 Dec 2009
Jia Wei-Hua, Pan Qing-Hua, Qin Hai-De, Xu Ya-Fei, Shen Guo-Ping, Chen Lina, Chen Li-Zhen, Feng Qi-Sheng, Hong Ming-Huang, Zeng Yi-Xin, Shugart Yin Yao
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is rare in most parts of the world but is more prevalent in Southern China, especially in Guangdong. The cytochrome P450 2E1 (CYP2E1) has been recognized as one of the critically important enzymes involved in oxidizing carcinogens and is probably to be associated with NPC carcinogenesis. To systematically investigate the association between genetic variants in CYP2E1 and NPC risk in...
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