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Fluorescence Sheds Light on DNA Damage, DNA Repair, and Mutations.

Trends in cancer - 1 Mar 2021

Owiti Norah A, Nagel Zachary D, Engelward Bevin P

Abstract excerpt

DNA damage can lead to carcinogenic mutations and toxicity that promotes diseases. Therefore, having rapid assays to quantify DNA damage, DNA repair, mutations, and cytotoxicity is broadly relevant to health. For example, DNA damage assays can be used to screen chemicals for genotoxicity, and knowledge about DNA repair capacity has applications in precision prevention and in personalized medicine. Furthermore,...

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Identifiers

PMID: 33203608
DOI: 10.1016/j.trecan.2020.10.006
PMCID: PMC7889721

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