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Article

Ablation of NPFFR2 in Mice Reduces Response to Single Prolonged Stress Model

14 Nov 2020

Abstract excerpt

Mental stress is highly related to many clinical symptoms and disorders, as it activates the hypothalamic-pituitary-adrenocortical (HPA) axis to affect a wide variety of physiological functions. Furthermore, stress leads to the aberrations in HPA axis activity and disruptions of body homeostasis. It was previously shown that neuropeptide FF (NPFF) regulates the HPA axis through the activation of hypothalamus...

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PMID: 33202667
DOI: 10.3390/cells9112479

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