Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotype-Specific Transcriptomic Responses to Glucocorticoid Signaling in the Prefrontal Cortex and Dorsal Raphe Nucleus Following Chronic Social Stress.

International journal of molecular sciences - 20 Jul 2026

Ritter Polina, Shuliupova Anastasiia, Reshetnikov Vasiliy, Bondar Natalia

Abstract excerpt

Chronic stress produces marked individual differences in behavioral adaptation and glucocorticoid sensitivity, but the molecular basis of this variability remains poorly understood. Here, we examined transcriptional responses to glucocorticoid receptor activation after chronic social defeat stress (CSDS) in male C57BL/6J mice. Based on behavioral responses during social interaction, stressed animals were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dexamethasone
Share to Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Glucocorticoids

Share to Prefrontal Cortex

Share to Receptors, Glucocorticoid

Share to Stress, Psychological

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 42511784
DOI: 10.3390/ijms27146442
PMCID: PMC13410218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotype-Specific Transcriptomic Responses to Glucocorticoid Signaling in the Prefrontal Cortex and Dorsal Raphe Nucleus Following Chronic Social Stress.PMID 42511784Read ↗

Characterization of transcriptional profiles associated with stress-induced neuronal activation in Arc-GFP miceSemantic proximity Read ↗

Deep Phenotyping with Global Brain Activity and Plasticity Mapping Identify the Dorsal Raphe-Basolateral Amygdala Circuit as a Mediator of Adaptive Stress ResponsesSemantic proximity Read ↗

DiffBrainNet: differential analyses add new insights into the response to glucocorticoids at the level of genes, networks and brain regionsSemantic proximity Read ↗

A Meta-Analysis of the Effects of Chronic Stress on the Prefrontal Transcriptome in Animal Models and Convergence with Existing Human DataSemantic proximity Read ↗

Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male mice.Semantic proximity Read ↗

Epigenetic signatures of chronic social stress in stress-susceptible animalsSemantic proximity Read ↗

Transcriptomic profiles of susceptibility and resilience to stress in the amygdala and hippocampus of male ratsSemantic proximity Read ↗

Ablation of NPFFR2 in Mice Reduces Response to Single Prolonged Stress ModelSemantic proximity Read ↗

Stress-induced motivational impairment is marked by diminished frontocortical cellular communication and neuropeptide signalingSemantic proximity Read ↗

Transcriptomic analyses of humans and mice provide insights into depression.Semantic proximity Read ↗

Repeated social defeat promotes persistent inflammatory changes in splenic myeloid cells; decreased expression of β-arrestin-2 (ARRB2) and increased expression of interleukin-6 (IL-6)Semantic proximity Read ↗

Alternative splicing in mouse brains affected by psychological stress is enriched in the signaling, neural transmission and blood-brain barrier pathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.