Article
CD147 Expressed on Memory CD4+ T Cells Limits Th17 Responses in Patients With Rheumatoid Arthritis.
Frontiers in immunology - 1 Jan 2020
Miao Jinlin, Zhang Kui, Zheng Zhaohui, Zhang Rui, Lv Minghua, Guo Na, Xu Yingming, Han Qing, Chen Zhinan, Zhu Ping
Abstract excerpt
Rheumatoid arthritis (RA) is a common autoimmune disease in which T helper-type 17 (Th17) cells have been critically involved. CD147 is a T cell activation-associated molecule and is involved in T cell development. However, it remains unclear whether CD147 participates in Th17 responses in RA patients. In this study, we demonstrated that in both the RA and healthy controls (HC) groups, CD147 expression on CD4+ T...
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