Article
The role of circulating tumor cells and K-ras mutations in patients with locally advanced rectal cancer: a prospective study.
Molecular biology reports - 1 Dec 2020
Bahnassy Abeer A, Abdel-Azim Yasser A, Ezzat Somaya, Abdellateif Mona S, Zekri Abdel-Rahman N, Mohanad Marwa, Salama Asmaa, Khaled Hussein
Abstract excerpt
Rectal cancer is a common malignancy with a relatively poor prognosis. We assessed the possible prognostic and predictive role(s) of circulating tumor cells (CTCs) and K-ras mutations in locally advanced rectal carcinoma (LARC) patients. CTCs number and K-ras mutation status were assessed in the Peripheral blood and tumor tissue samples of 60 patients with LARC compared to control group (normal rectal mucosa)....
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