Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APOE Genotypes and Brain Imaging Classes in Normal Cognition, Mild Cognitive Impairment, and Alzheimer's Disease: A Longitudinal Study.

Current Alzheimer research - 1 Jan 2020

Camarda Cecilia, Torelli Paola, Pipia Carmela, Sottile Gianluca, Cilluffo Giovanna, Camarda Rosolino

Abstract excerpt

OBJECTIVE: To evaluate in 419 stroke-free cognitively normal subjects (CN) aged 45-82 years covering during a long prospective study (11.54 ± 1.47 years) the preclinical to dementia spectrum: 1) the distribution of small vessel disease (V) and brain atrophy (A) aggregated as following: V-/A-, V-/A+, V+/A-, V+/A+; 2) the relationship of these imaging classes with individual apolipoprotein E (APOE) genotypes; 3)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Cognitive Dysfunction

Share to Longitudinal Studies

Share to Magnetic Resonance Imaging

Share to Neuroimaging

Share to Neuropsychological Tests

Source

Identifiers

PMID: 33167837
DOI: 10.2174/1567205017666201109093314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APOE Genotypes and Brain Imaging Classes in Normal Cognition, Mild Cognitive Impairment, and Alzheimer's Disease: A Longitudinal Study.PMID 33167837Read ↗

Associations between APOE genotype and cerebral small-vessel disease: a longitudinal study.Semantic proximity Read ↗

Protective effects of APOE e2 against disease progression in subcortical vascular mild cognitive impairment patients: A three-year longitudinal study.Semantic proximity Read ↗

The Value of Brain Structural Magnetic Resonance Imaging Combined with APOE--ε4 Genotype in Early Diagnosis and Disease Progression of Senile Vascular Cognitive Impairment No Dementia.Semantic proximity Read ↗

Apolipoprotein ɛ4 is Associated with Dementia and Cognitive Impairment Predominantly Due to Alzheimer's Disease and Not with Vascular Cognitive Impairment: A Singapore-Based Cohort.Semantic proximity Read ↗

Association between apolipoprotein E gene polymorphism and early MR findings in individuals with acute intracerebral hemorrhage: A retrospective cohort analysis.Semantic proximity Read ↗

Association between APOE ε2 and Aβ burden in patients with Alzheimer- and vascular-type cognitive impairment.Semantic proximity Read ↗

Dysexecutive versus amnestic Alzheimer disease subgroups: analysis of demographic, genetic, and vascular factors.Semantic proximity Read ↗

APOE-dependent phenotypes in subjects with mild cognitive impairment converting to Alzheimer's disease.Semantic proximity Read ↗

APOE <i>4 genotype, blood-brain barrier leakage, ischaemic stroke subtype and location</i>Semantic proximity Read ↗

Inherited risk of dementia and the progression of cerebral small vessel disease and inflammatory markers in cognitively healthy midlife adults: the PREVENT-Dementia study.Semantic proximity Read ↗

Cerebral small vessel disease in middle age and genetic predisposition to late-onset Alzheimer's disease.Semantic proximity Read ↗

APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.