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Article

Generating amphioxus Hedgehog knockout mutants and phenotype analysis.

Yi chuan = Hereditas - 1 Oct 2015

Wang Hui, Li Guang, Wang Yi-quan

Abstract excerpt

The amphioxus is a promising animal model for evolutionary-developmental studies due to its key position on the animal phylogenetic tree. In the present study, we reported a genetically modified amphioxus strain on the Hedgehog (Hh) gene locus using the TALEN method. The result showed that our TALEN pair injection could bring about 34% mutations in the amphioxus Hh coding region. Further analysis on the F(0)...

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PMID: 26496756
DOI: 10.16288/j.yczz.15-276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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