Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spontaneous motor-behavior abnormalities in two Drosophila models of neurodevelopmental disorders.

Journal of neurogenetics - 1 Mar 2021

Andrew David R, Moe Mariah E, Chen Dailu, Tello Judith A, Doser Rachel L, Conner William E, Ghuman Jaswinder K, Restifo Linda L

Abstract excerpt

Mutations in hundreds of genes cause neurodevelopmental disorders with abnormal motor behavior alongside cognitive deficits. Boys with fragile X syndrome (FXS), a leading monogenic cause of intellectual disability, often display repetitive behaviors, a core feature of autism. By direct observation and manual analysis, we characterized spontaneous-motor-behavior phenotypes of Drosophila dfmr1 mutants, an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Behavior, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Drosophila Proteins

Share to Fragile X Syndrome

Share to Locomotion

Share to Motor Activity

Share to Neurodevelopmental Disorders

Source

Identifiers

PMID: 33164597
DOI: 10.1080/01677063.2020.1833005

Genes

CASK
NLGN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spontaneous motor-behavior abnormalities in two Drosophila models of neurodevelopmental disorders.PMID 33164597Read ↗

Neurofibromin Loss of Function Drives Excessive Grooming in Drosophila.Semantic proximity Read ↗

Circadian Rhythm and Sleep Analyses in a Fruit Fly Model of Fragile X Syndrome Using a Video-Based Automated Behavioral Research System.Semantic proximity Read ↗

The role of Fragile X in the control of vertebrate spinal cord networksSemantic proximity Read ↗

Comprehensive Analysis of Two <i>Shank3</i> and the Cacna1c Mouse Models of Autism Spectrum DisorderSemantic proximity Read ↗

Fragile X mice have robust mGluR5-dependent alterations of social behaviour in the Automated Tube Test.Semantic proximity Read ↗

Circadian Rhythm and Sleep Analyses in a Fruit Fly Model of Fragile X Syndrome Using a Video-Based Automated Behavioral Research SystemSemantic proximity Read ↗

Deep phenotyping reveals movement phenotypes in mouse neurodevelopmental models.Semantic proximity Read ↗

Exploring Behavioral and Neural Dynamics of Social Interactions during the Juvenile Stage in a Mouse Model of Fragile X SyndromeSemantic proximity Read ↗

Systematic analysis of goal-related movement sequences during maternal behavior in a female mouse model for Rett syndromeSemantic proximity Read ↗

Sex-specific control of locomotor behavior by neuronal Arhgef10 in aged <i>Drosophila</i>Semantic proximity Read ↗

Day-to-day spontaneous social behaviours is quantitatively and qualitatively affected in a 16p11.2 deletion mouse modelSemantic proximity Read ↗

The behavioral phenotype of FMR1 mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.