Article

Sex-specific control of locomotor behavior by neuronal Arhgef10 in aged <i>Drosophila</i>

2025-12-21

Abstract excerpt

<h4>ABSTRACT</h4> Mutations and polymorphisms in the Rho guanine nucleotide exchange factor 10 ( ARHGEF10 ) locus are associated with behavioral and locomotor dysfunctions in humans, including psychiatric disorders and polyneuropathies that show age- and sex-specific prevalence. ARHGEF10 encodes a conserved guanine exchange factor that activates Rho GTPases and has proposed roles in cell migration and adhesion...

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Literature Corpus work: f2cd92ef-0ebb-5330-bcdb-6fd546c4b9fb
DOI: 10.64898/2025.12.18.694955

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