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Identification of two novel mutations in human acute myeloid leukemia cases.

Leukemia & lymphoma - 1 Feb 2021

O'Brien Gráinne, Zyla Joanna, Manola Kalliopi N, Pagoni Maria N, Polanska Joanna, Badie Christophe

Abstract excerpt

Acute myeloid leukemia (AML) is an aggressive cancer that progresses rapidly with a poor prognosis. Cytogenetic analysis provides the most accurate determination of diagnosis and prognosis however, about 42-48% of AML patients have a cytogenetically normal karyotype. Genetic analysis can provide further information and the identification of new mutations could result in improved risk stratification, prognosis and...

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PMID: 33161783
DOI: 10.1080/10428194.2020.1832664

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