Article
Novel Mutations in UTS2R are Associated with Adolescent Idiopathic Scoliosis in the Chinese Population.
Spine - 1 Mar 2021
Dai Zhicheng, Wang Yuwen, Wu Zhichong, Feng Zhenhua, Liu Zhen, Qiu Yong, Cheng Jack Chun-Yiu, Xu Leilei, Zhu Zezhang
Abstract excerpt
STUDY DESIGN: A case-control study. OBJECTIVES: To investigate the association of urotensin II (UTS2) signals with the susceptibility of adolescent idiopathic scoliosis (AIS) in the Chinese Han population. SUMMARY OF BACKGROUND DATA: Dysregulated UTS2 signals induced by impaired cerebrospinal fluid flow have been implicated in the development of idiopathic scoliosis through studies on zebrafish. Furthermore,...
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