Article
Theta-Defensins Inhibit High-Risk Human Papillomavirus Infection Through Charge-Driven Capsid Clustering.
Frontiers in immunology - 1 Jan 2020
Skeate Joseph G, Segerink Wouter H, Garcia Mauricio D, Fernandez Daniel J, Prins Ruben, Lühen Kim P, Voss Féline O, Da Silva Diane M, Kast W Martin
Abstract excerpt
Persistent infection with high-risk human papillomavirus (hrHPV) genotypes results in a large number of anogenital and head and neck cancers worldwide. Although prophylactic vaccination coverage has improved, there remains a need to develop methods that inhibit viral transmission toward preventing the spread of HPV-driven disease. Defensins are a class of innate immune effector peptides that function to protect...
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