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Article

Human alpha-defensins block papillomavirus infection.

Proceedings of the National Academy of Sciences of the United States of America - 31 Jan 2006

Buck Christopher B, Day Patricia M, Thompson Cynthia D, Lubkowski Jacek, Lu Wuyuan, Lowy Douglas R, Schiller John T

Abstract excerpt

Sexually transmitted human papillomaviruses (HPVs) are the primary cause of cervical cancer. Recent advances in techniques for production of papillomaviral vectors [known as pseudoviruses (PsVs)] have made it possible to perform high-throughput screens for compounds that might block the initial stages of papillomavirus infection. We have used PsVs to screen a variety of compounds that might function as inhibitors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16432216
DOI: 10.1073/pnas.0508033103
PMCID: PMC1360544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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