Pathogenesis of chronic lymphocytic leukemia and the development of novel therapeutic strategies.

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in Western countries and is characterized by the clonal expansion of mature CD5+ B cells. There have been substantial advances in the field of CLL research in the last decade, including the identification of recurrent mutations, and clarification of clonal architectures, signaling molecules, and the multistep leukemogenic process, providing a...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Carcinogenesis
• Share to Leukemia, Lymphocytic, Chronic, B-Cell