Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of Connexin Gap Junctions and Hemichannels by Calcium and Calcium Binding Protein Calmodulin.

International journal of molecular sciences - 2 Nov 2020

Hu Zhengping, Riquelme Manuel A, Gu Sumin, Jiang Jean X

Abstract excerpt

Connexins are the structural components of gap junctions and hemichannels that mediate the communication and exchange of small molecules between cells, and between the intracellular and extracellular environment, respectively. Connexin (Cx) 46 is predominately expressed in lens fiber cells, where they function in maintaining the homeostasis and transparency of the lens. Cx46 mutations are associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium
Share to Calcium-Binding Proteins
Share to Calmodulin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Connexins

Share to Gap Junctions

Share to Homeostasis

Share to Lens, Crystalline

Share to Protein Structure, Secondary

Source

Open in PubMed Open full text

Identifiers

PMID: 33147690
DOI: 10.3390/ijms21218194
PMCID: PMC7663298

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of Connexin Gap Junctions and Hemichannels by Calcium and Calcium Binding Protein Calmodulin.PMID 33147690Read ↗

Gating of cx46 gap junction hemichannels by calcium and voltage.Semantic proximity Read ↗

Connexin Mutants Compromise the Lens Circulation and Cause Cataracts through Biomineralization.Semantic proximity Read ↗

Connexin hemichannels in the lensSemantic proximity Read ↗

Disruption of the lens circulation causes calcium accumulation and precipitates in connexin mutant mice.Semantic proximity Read ↗

Gap Junction Channelopathies and Calmodulinopathies. Do Disease-Causing Calmodulin Mutants Affect Direct Cell-Cell Communication?Semantic proximity Read ↗

Focus on lens connexins.Semantic proximity Read ↗

Hemichannel and junctional properties of connexin 50.Semantic proximity Read ↗

Modulation of Cx46 hemichannels by nitric oxide.Semantic proximity Read ↗

Pathological hemichannels associated with human Cx26 mutations causing Keratitis-Ichthyosis-Deafness syndrome.Semantic proximity Read ↗

Gap Junctions or Hemichannel-Dependent and Independent Roles of Connexins in Fibrosis, Epithelial–Mesenchymal Transitions, and Wound HealingSemantic proximity Read ↗

The connexin46 mutant, Cx46T19M, causes loss of gap junction function and alters hemi-channel gating.Semantic proximity Read ↗

Dominant cataracts result from incongruous mixing of wild-type lens connexins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.