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Article

Modulation of Cx46 hemichannels by nitric oxide.

American journal of physiology. Cell physiology - 1 Jun 2009

Retamal Mauricio A, Yin ShengYong, Altenberg Guillermo A, Reuss Luis

Abstract excerpt

Gap-junction hemichannels are composed of six protein subunits (connexins). Undocked hemichannels contribute to physiological autocrine/paracrine cell signaling, including release of signaling molecules, cell-volume regulation, and glucose uptake. In addition, hemichannels may be pathologically activated by dephosphorylation and cell-membrane depolarization. Such hemichannel opening may induce and/or accelerate...

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Identifiers

PMID: 19357237
DOI: 10.1152/ajpcell.00054.2009
PMCID: PMC2692414

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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