Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modulation of Cx46 hemichannels by nitric oxide.

American journal of physiology. Cell physiology - 1 Jun 2009

Retamal Mauricio A, Yin ShengYong, Altenberg Guillermo A, Reuss Luis

Abstract excerpt

Gap-junction hemichannels are composed of six protein subunits (connexins). Undocked hemichannels contribute to physiological autocrine/paracrine cell signaling, including release of signaling molecules, cell-volume regulation, and glucose uptake. In addition, hemichannels may be pathologically a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cataract
Share to Connexin 43
Share to Dithiothreitol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Dyes

Share to Gap Junctions

Share to Nitric Oxide

Share to Nitric Oxide Donors

Share to Permeability

Source

Open in PubMed Open full text

Identifiers

PMID: 19357237
DOI: 10.1152/ajpcell.00054.2009
PMCID: PMC2692414

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19357237-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modulation of Cx46 hemichannels by nitric oxide.PMID 19357237Read ↗

Gating of cx46 gap junction hemichannels by calcium and voltage.Semantic proximity Read ↗

Regulation of Connexin Gap Junctions and Hemichannels by Calcium and Calcium Binding Protein Calmodulin.Semantic proximity Read ↗

Alterations at Arg76 of human connexin 46, a residue associated with cataract formation, cause loss of gap junction formation but preserve hemichannel function.Semantic proximity Read ↗

Hemichannel and junctional properties of connexin 50.Semantic proximity Read ↗

Connexin hemichannels in the lensSemantic proximity Read ↗

The connexin46 mutant, Cx46T19M, causes loss of gap junction function and alters hemi-channel gating.Semantic proximity Read ↗

Connexin46 mutations linked to congenital cataract show loss of gap junction channel function.Semantic proximity Read ↗

Different consequences of cataract-associated mutations at adjacent positions in the first extracellular boundary of connexin50.Semantic proximity Read ↗

Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutantSemantic proximity Read ↗

Connexin26 hemichannels with a mutation that causes KID syndrome in humans lack sensitivity to CO2.Semantic proximity Read ↗

Rational design of new NO and redox sensitivity into connexin26 hemichannels.Semantic proximity Read ↗

Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.