Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Chaperones: A Double-Edged Sword in Neurodegenerative Diseases

6 Oct 2020

Abstract excerpt

Aberrant accumulation of misfolded proteins into amyloid deposits is a hallmark in many age-related neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS). Pathological inclusions and the associated toxicity appear to spread through the nervous system in a characteristic pattern during the disease. This has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Endoplasmic Reticulum Stress and Disease
Share to Prion Diseases and Protein Misfolding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33132902
DOI: 10.3389/fnagi.2020.581374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Chaperones: A Double-Edged Sword in Neurodegenerative DiseasesPMID 33132902Read ↗

Dealing with misfolded proteins: examining the neuroprotective role of molecular chaperones in neurodegeneration.Semantic proximity Read ↗

Protein-misfolding diseases and chaperone-based therapeutic approaches.Semantic proximity Read ↗

Roles of molecular chaperones in protein misfolding diseases.Semantic proximity Read ↗

The role of HSP70 and its co-chaperones in protein misfolding, aggregation and disease.Semantic proximity Read ↗

Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic InterventionSemantic proximity Read ↗

Alzheimer's Disease and Molecular Chaperones: Current Knowledge and the Future of ChaperonotherapySemantic proximity Read ↗

Putative Roles and Therapeutic Potential of the Chaperone System in Amyotrophic Lateral Sclerosis and Multiple SclerosisSemantic proximity Read ↗

Protein folding alterations in amyotrophic lateral sclerosis.Semantic proximity Read ↗

Prions: generation and spread versus neurotoxicity.Semantic proximity Read ↗

Mechanisms of protein-folding diseases at a glance.Semantic proximity Read ↗

Molecular chaperones: multiple functions, pathologies, and potential applications.Semantic proximity Read ↗

Protein misfolding in the late-onset neurodegenerative diseases: common themes and the unique case of amyotrophic lateral sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.