Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein-misfolding diseases and chaperone-based therapeutic approaches.

The FEBS journal - 1 Apr 2006

Chaudhuri Tapan K, Paul Subhankar

Abstract excerpt

A large number of neurodegenerative diseases in humans result from protein misfolding and aggregation. Protein misfolding is believed to be the primary cause of Alzheimer's disease, Parkinson's disease, Huntington's disease, Creutzfeldt-Jakob disease, cystic fibrosis, Gaucher's disease and many other degenerative and neurodegenerative disorders. Cellular molecular chaperones, which are ubiquitous, stress-induced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid
Share to Models, Molecular
Share to Molecular Chaperones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Neurodegenerative Diseases

Share to Protein Conformation

Share to Protein Folding

Share to PrPSc Proteins

Source

Identifiers

PMID: 16689923
DOI: 10.1111/j.1742-4658.2006.05181.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein-misfolding diseases and chaperone-based therapeutic approaches.PMID 16689923Read ↗

Dealing with misfolded proteins: examining the neuroprotective role of molecular chaperones in neurodegeneration.Semantic proximity Read ↗

Roles of molecular chaperones in protein misfolding diseases.Semantic proximity Read ↗

Molecular Chaperones: A Double-Edged Sword in Neurodegenerative DiseasesSemantic proximity Read ↗

Screening methods for identifying pharmacological chaperones.Semantic proximity Read ↗

Mechanisms of protein-folding diseases at a glance.Semantic proximity Read ↗

The role of HSP70 and its co-chaperones in protein misfolding, aggregation and disease.Semantic proximity Read ↗

Protein misfolding in neurodegenerative diseases: implications and strategiesSemantic proximity Read ↗

[Pharmacological chaperones: a potential therapeutic treatment for conformational diseases].Semantic proximity Read ↗

Chaperone therapy for lysosomal and non-lysosomal protein misfolding diseases.Semantic proximity Read ↗

Molecular mechanisms of proteinopathies across neurodegenerative disease: a reviewSemantic proximity Read ↗

Emerging novel concept of chaperone therapies for protein misfolding diseases.Semantic proximity Read ↗

Protein folding alterations in amyotrophic lateral sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.