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Article

The prophage-encoded hyaluronate lyase has broad substrate specificity and is regulated by the N-terminal domain.

The Journal of biological chemistry - 19 Dec 2014

Singh Sudhir Kumar, Bharati Akhilendra Pratap, Singh Neha, Pandey Praveen, Joshi Pankaj, Singh Kavita, Mitra Kalyan, Gayen Jiaur R, Sarkar Jayanta, Akhtar Md Sohail

Abstract excerpt

Streptococcus equi is the causative agent of the highly contagious disease "strangles" in equines and zoonotic meningitis in human. Spreading of infection in host tissues is thought to be facilitated by the bacterial gene encoded extracellular hyaluronate lyase (HL), which degrades hyaluronan (HA), chondroitin 6-sulfate, and dermatan sulfate of the extracellular matrix). The clinical strain S. equi 4047 however,...

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Identifiers

PMID: 25378402
DOI: 10.1074/jbc.M113.507673
PMCID: PMC4271211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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