Article
Serum concentration of interleukin-35 and its association with tumor stages and FOXP3 gene polymorphism in patients with prostate cancer.
Cytokine - 1 Jan 2019
Chatrabnous Nazanin, Ghaderi Abass, Ariafar Ali, Razeghinia Mohammad Sadegh, Nemati Maryam, Jafarzadeh Abdollah
Abstract excerpt
IL-35 is an immunosuppressive cytokine that is largely synthesized by regulatory T (Treg) cells and may inhibit antitumor immune responses. This investigation aimed to determine the serum IL-35 concentrations and a single nucleotide polymorphism (SNP) in position of rs3761548, within the promoter region of FOXP3 gene, in patients with prostate cancer (PC). The blood specimens were obtained from 150 PC patients...
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