Article
Inferring evolutionary pathways and directed genotype networks of foodborne pathogens.
PLoS computational biology - 1 Oct 2020
Cliff Oliver M, McLean Natalia, Sintchenko Vitali, Fair Kristopher M, Sorrell Tania C, Kauffman Stuart, Prokopenko Mikhail
Abstract excerpt
Modelling the emergence of foodborne pathogens is a crucial step in the prediction and prevention of disease outbreaks. Unfortunately, the mechanisms that drive the evolution of such continuously adapting pathogens remain poorly understood. Here, we combine molecular genotyping with network science and Bayesian inference to infer directed genotype networks-and trace the emergence and evolutionary paths-of...
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