Article
Neoantimon: a multifunctional R package for identification of tumor-specific neoantigens.
Bioinformatics (Oxford, England) - 15 Sept 2020
Hasegawa Takanori, Hayashi Shuto, Shimizu Eigo, Mizuno Shinichi, Niida Atsushi, Yamaguchi Rui, Miyano Satoru, Nakagawa Hidewaki, Imoto Seiya
Abstract excerpt
SUMMARY: It is known that some mutant peptides, such as those resulting from missense mutations and frameshift insertions, can bind to the major histocompatibility complex and be presented to antitumor T cells on the surface of a tumor cell. These peptides are termed neoantigen, and it is important to understand this process for cancer immunotherapy. Here, we introduce an R package termed Neoantimon that can...
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