Article
Expansion of CD4+ CD25+ FoxP3+ regulatory T cells in chronic hepatitis C virus infection.
Iranian journal of immunology : IJI - 1 Sept 2010
Hashempoor Tayebeh, Bamdad Taravat, Merat Shahin, Janzamin Ehsan, Nemati Leila, Jabbari Hossain, Sharifi Amir-Houshang, Zamini Hediyeh
Abstract excerpt
BACKGROUND: Regulatory T cells (Tregs) have been involved in impaired immunity and may have a pivotal role in persistence of viral infections. OBJECTIVE: To develop a simple and reliable in-house three color flow cytometery of peripheral blood to understand the role of HCV infection in the increase of Tregs. METHODS: The level of naturally occurring CD4+ CD25+ FoxP3+ regulatory T cells (nTregs) in 20 chronically...
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