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Immunosenescence markers in T- and NK-cells according to the CD4/CD8 ratio in successfully treated people living with HIV

15 Apr 2025

Abstract excerpt

Introduction The CD4/CD8 ratio has emerged as a useful indicator of immune dysfunction and comorbid conditions in people living with HIV (PLWH). However, its optimal cut-off value is unclear. We explored the correlation between the CD4/CD8 ratio, immunosenescence markers and comorbid conditions. Methods We prospectively included PLWH on successful and stable ART (antiretroviral therapy) > 60 years old and...

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Identifiers

PMID: 40303366
DOI: 10.3389/fmed.2025.1562537

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