Article
HIV infection-related premature immunosenescence: high rates of immune exhaustion after short time of infection.
Current HIV research - 1 Jul 2011
Ferrando-Martínez Sara, Ruiz-Mateos Ezequiel, Romero-Sánchez María Concepción, Muñoz-Fernández M Ángeles, Viciana Pompeyo, Genebat Miguel, Leal Manuel
Abstract excerpt
Premature immunosenescence has been reported in different HIV scenarios. However, how premature is the HIV-related immunosenescent phenotype is still unknown. Thus, the aim of this study was to analyze the immunosenescent status of young viraemic naive HIV-infected individuals, with less than four years from infection. To this end, replicative senescence, activation and proliferation T-cell levels were analyzed...
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