Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhancement of HIV-1 Env-Specific CD8 T Cell Responses Using Interferon-Stimulated Gene 15 as an Immune Adjuvant.

Journal of virology - 22 Dec 2020

Gómez Carmen Elena, Perdiguero Beatriz, Falqui Michela, Marín María Q, Bécares Martina, Sorzano Carlos Óscar S, García-Arriaza Juan, Esteban Mariano, Guerra Susana

Abstract excerpt

Induction of the endogenous innate immune system by interferon (IFN) triggers the expression of many proteins that serve like alarm bells in the body, activating an immune response. After a viral infection, one of the genes activated by IFN induction is the IFN-stimulated gene 15 (ISG15), which encodes a ubiquitin-like protein that undergoes a reversible posttranslational modification (ISGylation). ISG15 protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adjuvants, Immunologic
Share to AIDS Vaccines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Antibodies

Share to Immunization, Secondary

Share to Immunomodulation

Share to Ubiquitins

Share to Vaccines, Synthetic

Share to Vaccinia virus

Source

Open in PubMed Open full text

Identifiers

PMID: 33115866
DOI: 10.1128/JVI.01155-20
PMCID: PMC7944454

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhancement of HIV-1 Env-Specific CD8 T Cell Responses Using Interferon-Stimulated Gene 15 as an Immune Adjuvant.PMID 33115866Read ↗

Ubiquitin-like Molecule ISG15 Acts as an Immune Adjuvant to Enhance Antigen-specific CD8 T-cell Tumor Immunity.Semantic proximity Read ↗

ISG15 facilitates cellular antiviral response to dengue and west nile virus infection in vitroSemantic proximity Read ↗

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis virusesSemantic proximity Read ↗

Emerging Roles for Immunomodulatory Functions of Free ISG15Semantic proximity Read ↗

ISGylation in Innate Antiviral Immunity and Pathogen Defense Responses: A ReviewSemantic proximity Read ↗

Identification of Interferon-Stimulated Gene 15 as an Antiviral Molecule during Sindbis Virus Infection In VivoSemantic proximity Read ↗

ISG15 Functions as an Interferon-Mediated Antiviral Effector Early in the Murine Norovirus Life CycleSemantic proximity Read ↗

ISG15 driven cellular responses to virus infectionSemantic proximity Read ↗

ISG15 Arg151 and the ISG15-Conjugating Enzyme UbE1L Are Important for Innate Immune Control of Sindbis VirusSemantic proximity Read ↗

ISG15 Modulates Type I Interferon Signaling and the Antiviral Response during Hepatitis E Virus ReplicationSemantic proximity Read ↗

Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infectionSemantic proximity Read ↗

ISG-15, beyond its functions in the cell: a mini reviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.