Article
Immune molecular profiling of a multiresistant primary prostate cancer with a neuroendocrine-like phenotype: a case report.
BMC urology - 28 Oct 2020
Williams Scott G, Aw Yeang Han Xian, Mitchell Catherine, Caramia Franco, Byrne David J, Fox Stephen B, Haupt Sue, Schittenhelm Ralf B, Neeson Paul J, Haupt Ygal, Keam Simon P
Abstract excerpt
BACKGROUND: Understanding the drivers of recurrence in aggressive prostate cancer requires detailed molecular and genomic understanding in order to aid therapeutic interventions. We provide here a case report of histological, transcriptional, proteomic, immunological, and genomic features in a longitudinal study of multiple biopsies from diagnosis, through treatment, and subsequent recurrence. CASE PRESENTATION:...
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