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Article

Ascertainment Bias in the Association Between Elevated Lipoprotein(a) and Familial Hypercholesterolemia.

Journal of the American College of Cardiology - 2 Jun 2020

Trinder Mark, DeCastro Maria L, Azizi Hawmid, Cermakova Luba, Jackson Linda M, Frohlich Jiri, Mancini G B John, Francis Gordon A, Brunham Liam R

Abstract excerpt

BACKGROUND: Lipoprotein(a) is an atherogenic low-density lipoprotein-like particle and circulating levels are largely determined by genetics. Patients with familial hypercholesterolemia (FH) have elevated lipoprotein(a); however, it remains unclear why. OBJECTIVES: This study compared the levels of lipoprotein(a) and associated genetic factors between individuals that were ascertained for FH clinically versus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32466883
DOI: 10.1016/j.jacc.2020.03.065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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