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Article

Significance of lipoprotein(a) levels in familial hypercholesterolemia and coronary artery disease.

Atherosclerosis - 1 May 2017

Li Sha, Wu Na-Qiong, Zhu Cheng-Gang, Zhang Yan, Guo Yuan-Lin, Gao Ying, Li Xiao-Lin, Qing Ping, Cui Chuan-Jue, Xu Rui-Xia, Sun Jing, Liu Geng, Dong Qian, Li Jian-Jun

Abstract excerpt

BACKGROUND AND AIMS: Patients with familial hypercholesterolemia (FH) are often characterized by premature coronary artery disease (CAD) with heterogeneity at onset. The aim of the present study was to investigate the associations of lipoprotein (a) [Lp(a)] with the FH phenotype, genotype and roles of Lp(a) in determining CAD risk among patients with and without FH. METHODS: We enrolled 8050 patients undergoing...

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Identifiers

PMID: 28351002
DOI: 10.1016/j.atherosclerosis.2017.03.021

Genes

CAD
LDLR
APOB
PCSK9

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