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Doxorubicin Improves Cancer Cell Targeting by Filamentous Phage Gene Delivery Vectors

23 Oct 2020

Abstract excerpt

Merging targeted systemic gene delivery and systemic chemotherapy against cancer, chemovirotherapy, has the potential to improve chemotherapy and gene therapy treatments and overcome cancer resistance. We introduced a bacteriophage (phage) vector, named human adeno-associated virus (AAV)/phage or AAVP, for the systemic targeting of therapeutic genes to cancer. The vector was designed as a hybrid between a...

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PMID: 33114050
DOI: 10.3390/ijms21217867

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