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Aging, senescence and mitochondria: the PGC-1/ERR axis

20 Oct 2020

Abstract excerpt

Aging is a degenerative process that results from the accumulation of cellular and tissue lesions, leading progressively to organ dysfunction and death. Although the biological basis of human aging remains unclear, a large amount of data points to deregulated mitochondrial function as a central regulator of this process. Mounting years of research on aging support the notion that the engendered age-related...

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PMID: 33112791
DOI: 10.1530/jme-20-0196

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