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Polyphenol-Based Therapeutic Strategies for Mitochondrial Dysfunction in Aging

3 Aug 2025

Abstract excerpt

Aging, a progressive and time-dependent decline in physiological functions, is driven by interconnected hallmarks, among which mitochondrial dysfunction plays a central role. Mitochondria not only regulate energy production but also play key roles in other cellular processes, including ROS generation, apoptosis, and metabolic signaling-all of which decline with aging. Polyphenols are a diverse group of natural...

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PMID: 40867561
DOI: 10.3390/biom15081116

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