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Environmental factors and risk of multiple sclerosis: Findings from meta-analyses and Mendelian randomization studies

6 Sept 2019

Abstract excerpt

Multiple sclerosis (MS) is a chronic demyelinating disease that is associated with permanent disability and low quality of life. Development of MS is attributed to a combination of genetic and environmental factors. Genome-wide association studies revealed more than 200 variants that are associated with risk of MS. An umbrella review showed that smoking, history of infectious mononucleosis, and anti-Epstein-Barr...

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PMID: 32249718
DOI: 10.1177/1352458519872664

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