Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel bioassay for quantification of surface Cannabinoid receptor 1 expression.

Scientific reports - 23 Oct 2020

Rodríguez-Rodríguez Ismael, Kalafut Joanna, Czerwonka Arkadiusz, Rivero-Müller Adolfo

Abstract excerpt

The cannabinoid receptor type 1 (CB1) plays critical roles in multiple physiological processes such as pain perception, brain development and body temperature regulation. Mutations on this gene (CNR1), results in altered functionality and/or biosynthesis such as reduced membrane expression, changes in mRNA stability or changes in downstream signaling that act as triggers for diseases such as obesity, Parkinson's,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Assay
Share to Corpus Striatum
Share to HEK293 Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Polymorphism, Genetic

Share to Receptor, Cannabinoid, CB1

Share to Reproducibility of Results

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 33097803
DOI: 10.1038/s41598-020-75331-y
PMCID: PMC7584592

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel bioassay for quantification of surface Cannabinoid receptor 1 expression.PMID 33097803Read ↗

Cannabinoid Receptor Signaling is Dependent on Sub-Cellular LocationSemantic proximity Read ↗

Protein Interactors and Trafficking Pathways That Regulate the Cannabinoid Type 1 Receptor (CB1R)Semantic proximity Read ↗

Recent progress in assays for GPCR drug discoverySemantic proximity Read ↗

Drug Derived Fluorescent Probes for the Specific Visualization of Cannabinoid Type 2 Receptor - A Toolbox ApproachSemantic proximity Read ↗

Phenotypic screening of cannabinoid receptor 2 ligands shows different sensitivity to genotype.Semantic proximity Read ↗

Identification and characterisation of a novel splice variant of the human CB1 receptorSemantic proximity Read ↗

Functional characterization of putative cholesterol binding sequence (CRAC) in human type-1 cannabinoid receptor.Semantic proximity Read ↗

Involvement of the carboxyl terminus of the third intracellular loop of the cannabinoid CB1 receptor in constitutive activation of Gs.Semantic proximity Read ↗

A fluorescent sensor for spatiotemporally resolved endocannabinoid dynamics <i>in vitro</i> and <i>in vivo</i>Semantic proximity Read ↗

Targeting the cannabinoid CB2 receptor: mutations, modeling and development of CB2 selective ligands.Semantic proximity Read ↗

Discrimination of the Activity of Low-Affinity Wild-Type and High-Affinity Mutant Recombinant BoNT/B by a SIMA Cell-Based Reporter Release Assay.Semantic proximity Read ↗

Picomolar-Level Sensing of Cannabidiol by Metal Nanoparticles Functionalized with Chemically Induced Dimerization BindersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.