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Article

Paraoxonase 1 polymorphisms are not related with the risk for multiple sclerosis.

Neuromolecular medicine - 1 Sept 2010

Martínez Carmen, García-Martín Elena, Benito-León Julián, Calleja Patricia, Díaz-Sánchez María, Pisa Diana, Alonso-Navarro Hortensia, Ayuso-Peralta Lucía, Torrecilla Dolores, Agúndez José A G, Jiménez-Jiménez Félix Javier

Abstract excerpt

It has been suggested a possible role of oxidative stress and lipid peroxidation in the inflammatory processes and in the pathogenesis of multiple sclerosis. Human serum paraoxonase 1 is a polymorphic enzyme encoded by the gene PON1, located in chromosome 7q21.3, that plays a major role in the metabolism of organophosporus compounds, and in the protection against oxidative stress. Paraoxonase-1 activity has been...

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Source

Identifiers

PMID: 19826962
DOI: 10.1007/s12017-009-8095-9

Genes

PON1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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